This question lacks nuance. Where do you draw the line? I'd draw one at suicide thoughts that you can't stop on your own and before seriously considering using any kind of psychoactive drugs for self-medication. Anything else IMO needs about as much medical intervention as a low fever case of common cold.
Oh, and once these two lines are back at comfortable distance you stop.
That's how most of the people in the world are, including the dearest friends and family. Most people's only motivation in life is to find a loophole to abuse. They will even convince themselves they are something they're not to achieve it.
This is just not an acceptable cultural viewpoint. Abusing a permissive system must be discouraged.